PDE Modeling of a Microfluidic Thermal Process for Genetic Analysis Application

This paper details the infinite dimensional dynamics of a prototype microfluidic thermal process that is used for genetic analysis purposes. Highly effective infinite dimensional dynamics, in addition to collocated sensor and actuator architecture, require the development of a precise control framew...

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Bibliographic Details
Main Authors: Reza Banaei Khosroushahi, Horacio J. Marquez, Jose Martinez-Quijada, Christopher J. Backhouse
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Applied Mathematics
Online Access:http://dx.doi.org/10.1155/2013/767853
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Summary:This paper details the infinite dimensional dynamics of a prototype microfluidic thermal process that is used for genetic analysis purposes. Highly effective infinite dimensional dynamics, in addition to collocated sensor and actuator architecture, require the development of a precise control framework to meet the very tight performance requirements of this system, which are not fully attainable through conventional lumped modeling and controller design approaches. The general partial differential equations describing the dynamics of the system are separated into steady-state and transient parts which are derived for a carefully chosen three-dimensional axisymmetric model. These equations are solved analytically, and the results are verified using an experimentally verified precise finite element method (FEM) model. The final combined result is a framework for designing a precise tracking controller applicable to the selected lab-on-a-chip device.
ISSN:1110-757X
1687-0042