Combined exosome of adipose-derived mesenchymal stem cell and hyaluronic acid delays early osteoarthritis progression of ovine sheep model: Clinical, radiographic, macroscopic and microscopic evaluation [version 3; peer review: 2 approved, 1 not approved]

Combined exosome of adipose-derived mesenchymal stem cell and hyaluronic acid delays early osteoarthritis progression of ovine sheep model: Clinical, radiographic, macroscopic and microscopic evaluation [version 3; peer review: 2 approved, 1 not approved]

Background Current treatment of osteoarthritis (OA) mainly focused on treating symptoms. Exosome from Adipose-derived Mesenchymal Stem Cell (Ad-MSC) have been shown to delay degenerative process. This study aimed to investigate the clinical, radiological and histological impact of combined intra-art...

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Main Authors: Marcel Prasetyo, Radiana Dhewayani Antarianto, Tri Isyani Tungga Dewi, Bambang Pontjo Priosoeryanto, Trevino Aristakus Pakasi, Angela Jennifer Tantry, Alida Harahap, Ismail Hadisoebroto Dilogo, Jessica Fiolin, Ludwig Andribert Powantia Pontoh
Format: Article
Language:English
Published: F1000 Research Ltd 2025-02-01
Series:F1000Research
Subjects:
exosome
adipose-derived Mesenchymal Stem Cell (Ad-MSC)
early osteoarthritis (OA)
clinical lameness score
radiographic OA score
Osteoarthritis Research Society International (OARSI) score
eng
Online Access:https://f1000research.com/articles/13-494/v3
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