Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial.

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial.

<h4>Background</h4>Experimental infection of malaria-naïve volunteers by the bite of Plasmodium falciparum-infected mosquitoes is a preferred means to test the protective effect of malaria vaccines and drugs. The standard model relies on the bite of five infected mosquitoes to induce mal...

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Bibliographic Details
Main Authors: Kirsten E Lyke, Matthew Laurens, Matthew Adams, Peter F Billingsley, Adam Richman, Mark Loyevsky, Sumana Chakravarty, Christopher V Plowe, B Kim Lee Sim, Robert Edelman, Stephen L Hoffman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0013490&type=printable
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