Novel antibiotics against Staphylococcus aureus without detectable resistance by targeting proton motive force and FtsH

Novel antibiotics against Staphylococcus aureus without detectable resistance by targeting proton motive force and FtsH

Abstract The increased prevalence of methicillin‐resistant Staphylococcus aureus (MRSA) and its biofilms poses a great threat to human health. Especially, S. aureus‐related osteomyelitis was hardly cured even by conventional antibiotics combined with surgical treatment. The development of novel stru...

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Bibliographic Details
Main Authors: She Pengfei, Yang Yifan, Li Linhui, Li Yimin, Xiao Dan, Guo Shaowei, Huang Guanqing, Wu Yong
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:MedComm
Subjects:
antibiotic development
methicillin‐resistant Staphylococcus aureus
biofilm
proton motive force
FtsH
in vivo
Online Access:https://doi.org/10.1002/mco2.70046
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