Effects of USP25 knockout on the gut microbial diversity and composition in mice

Effects of USP25 knockout on the gut microbial diversity and composition in mice

Abstract Background The gut microbiota plays a crucial role in host health. Recent study revealed that ubiquitin-specific protease 25 (USP25) deficiency affected colonic immune responses and resistance to certain bacterial infection. This study aimed to investigate the impact of USP25 gene deletion...

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Bibliographic Details
Main Authors: Jinqiu Li, Zhonghui Chen, Xingchen Yan, Qizhou Chen, Cirong Chen, Huan Liu, Jianlin Shen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Microbiology
Subjects:
USP25
Gut microbiota
16S rRNA sequencing
Metagenomic sequencing
Antibiotic resistance
Host-microbe interactions
Online Access:https://doi.org/10.1186/s12866-025-04035-y
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