Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

Osteosarcoma Cell‐Derived Migrasomes Promote Macrophage M2 Polarization to Aggravate Osteosarcoma Proliferation and Metastasis

Abstract The local tumor microenvironment (TME) of osteosarcoma (OS) includes several tumor niches that control tumor growth and cell extravasation. Migrasomes are recently discovered extracellular vesicles produced during cell migration. Herein, the results show OS cell production of migrasomes in...

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Bibliographic Details
Main Authors: Wanshun Liu, Lei Li, Xiaoming Bai, Mengxue Zhang, Wei Lv, Yongbin Ma, Yuzhi Sun, Hongjing Zhang, Qing Jiang, Qingqiang Yao, Zhi‐Yuan Zhang
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
macrophage
MFGE8
migrasome
osteosarcoma
Online Access:https://doi.org/10.1002/advs.202409870
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https://doi.org/10.1002/advs.202409870

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