Oxidative stress induces cortical stiffening and cytoskeletal remodelling in pre-apoptotic cancer cells

Oxidative stress induces cortical stiffening and cytoskeletal remodelling in pre-apoptotic cancer cells

An imbalanced production of reactive oxygen species (ROS) is linked to various aspects of cancer development, including cytoskeletal remodelling. However, the relationship between ROS, actin and cellular stiffness remains controversial. Here, we show that oxidative stress increases cortical stiffnes...

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Bibliographic Details
Main Authors: Aiman Jalmukhambetova, Aidana Baltabekova, Aizhan Tolebay, Nargiz Rakhimgerey, Ferdinand Molnár, Tri Thanh Pham, Agata N. Burska, Dos D. Sarbassov
Format: Article
Language:English
Published: Shared Science Publishers OG 2025-08-01
Series:Cell Stress
Subjects:
oxidative stress
cortical stiffness
atomic force microscopy
f-actin
arsenic trioxide and d form of vitamin c
cancer migration
Online Access:http://microbialcell.com/researcharticles/2025a-jalmukhambetova-cell-stress
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