Use of Anti-VEGF Agents in Glaucoma Surgery
A number of antivascular endothelial growth factor agents are currently used to treat ocular conditions. These agents have similar but distinct biologic qualities and have each been used in the management of neovascular glaucoma and in glaucoma surgery. Several different delivery methods are describ...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/1645269 |
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| _version_ | 1832552622447394816 |
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| author | Mark Slabaugh Sarwat Salim |
| author_facet | Mark Slabaugh Sarwat Salim |
| author_sort | Mark Slabaugh |
| collection | DOAJ |
| description | A number of antivascular endothelial growth factor agents are currently used to treat ocular conditions. These agents have similar but distinct biologic qualities and have each been used in the management of neovascular glaucoma and in glaucoma surgery. Several different delivery methods are described, and because these medications are routinely given as intraocular injections, there are some benefits over traditional antifibrotic medications when used in glaucoma surgery. These agents effectively induce regression of anterior segment neovascularization and facilitate initial surgical management of neovascular glaucoma but the long-term outcome of this condition remains dependent on definitive management of the underlying process. Use in trabeculectomy or tube shunt procedures for other types of glaucoma has shown promise in affecting bleb morphology but has not yet been found to be as effective as traditional antifibrotic agents. There are reports of persistently raised intraocular pressure after repeated use of the anti-VEGF agents, possibly related to frequency of injection. These medications have wide application in the field of surgical glaucoma but a precise role has yet to be defined. |
| format | Article |
| id | doaj-art-1f1ac8c181e741849cb0ebd3c5ac2a6b |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-1f1ac8c181e741849cb0ebd3c5ac2a6b2025-02-03T05:58:10ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/16452691645269Use of Anti-VEGF Agents in Glaucoma SurgeryMark Slabaugh0Sarwat Salim1Department of Ophthalmology, William H. Havener Eye Institute, The Ohio State University Medical Center, Columbus, OH, USADepartment of Ophthalmology, Medical College of Wisconsin, 925 N. 87th Street, Milwaukee, WI 53226, USAA number of antivascular endothelial growth factor agents are currently used to treat ocular conditions. These agents have similar but distinct biologic qualities and have each been used in the management of neovascular glaucoma and in glaucoma surgery. Several different delivery methods are described, and because these medications are routinely given as intraocular injections, there are some benefits over traditional antifibrotic medications when used in glaucoma surgery. These agents effectively induce regression of anterior segment neovascularization and facilitate initial surgical management of neovascular glaucoma but the long-term outcome of this condition remains dependent on definitive management of the underlying process. Use in trabeculectomy or tube shunt procedures for other types of glaucoma has shown promise in affecting bleb morphology but has not yet been found to be as effective as traditional antifibrotic agents. There are reports of persistently raised intraocular pressure after repeated use of the anti-VEGF agents, possibly related to frequency of injection. These medications have wide application in the field of surgical glaucoma but a precise role has yet to be defined.http://dx.doi.org/10.1155/2017/1645269 |
| spellingShingle | Mark Slabaugh Sarwat Salim Use of Anti-VEGF Agents in Glaucoma Surgery Journal of Ophthalmology |
| title | Use of Anti-VEGF Agents in Glaucoma Surgery |
| title_full | Use of Anti-VEGF Agents in Glaucoma Surgery |
| title_fullStr | Use of Anti-VEGF Agents in Glaucoma Surgery |
| title_full_unstemmed | Use of Anti-VEGF Agents in Glaucoma Surgery |
| title_short | Use of Anti-VEGF Agents in Glaucoma Surgery |
| title_sort | use of anti vegf agents in glaucoma surgery |
| url | http://dx.doi.org/10.1155/2017/1645269 |
| work_keys_str_mv | AT markslabaugh useofantivegfagentsinglaucomasurgery AT sarwatsalim useofantivegfagentsinglaucomasurgery |