Cell signaling communication within papillary craniopharyngioma revealed by an integrated analysis of single-cell RNA sequencing and bulk RNA sequencing

Cell signaling communication within papillary craniopharyngioma revealed by an integrated analysis of single-cell RNA sequencing and bulk RNA sequencing

Abstract Objective This study aims to elucidate the primary signaling communication among papillary craniopharyngioma (PCP) tumor cells. Methods Five samples of PCP were utilized for single-cell RNA sequencing. The most relevant ligand and receptor interactions among different cells were calculated...

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Bibliographic Details
Main Authors: Xiaoyue Zhu, Yanfei Jia, Zicheng Zhao, Xiaoyu Zhang, Yunlong Zhao, Songbai Gui, Xiu-An Yang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Papillary craniopharyngioma
Single-cell RNA sequencing
Fibroblasts
Communication
Online Access:https://doi.org/10.1186/s12967-025-06149-3
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https://doi.org/10.1186/s12967-025-06149-3

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