Emergence of Xin demarcates a key innovation in heart evolution.

The mouse Xin repeat-containing proteins (mXinalpha and mXinbeta) localize to the intercalated disc in the heart. mXinalpha is able to bundle actin filaments and to interact with beta-catenin, suggesting a role in linking the actin cytoskeleton to N-cadherin/beta-catenin adhesion. mXinalpha-null mou...

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Bibliographic Details
Main Authors: Shaun E Grosskurth, Debashish Bhattacharya, Qinchuan Wang, Jim Jung-Ching Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002857&type=printable
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