Serum microRNA expression quantitative trait loci in children with asthma colocalize with asthma-related GWAS results

Serum microRNA expression quantitative trait loci in children with asthma colocalize with asthma-related GWAS results

Abstract Asthma poses a significant public health burden. Despite identifying more than a hundred genetic risk loci in genome-wide association studies (GWAS), the underlying functional mechanisms remain poorly understood. Studying omics, especially microRNAs (miRNAs), is a promising approach to faci...

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Main Authors: Julian Hecker, Anshul Tiwari, Rinku Sharma, Kevin Mendez, Jiang Li, Sofina Begum, Qingwen Chen, Albert Smith, Juan C. Celedón, Scott T. Weiss, Rachel S. Kelly, Jessica A. Lasky-Su, Kelan G. Tantisira, Michael McGeachie
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-025-00510-7
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https://doi.org/10.1038/s41525-025-00510-7

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