Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016)
Background: The relationship between diabetes and heart failure significantly impacts public health. This study assessed the prognostic nutritional index (PNI) as a predictor of heart failure risk in adult diabetic patients. Metho...
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| Format: | Article |
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IMR Press
2025-01-01
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| Series: | Reviews in Cardiovascular Medicine |
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| Online Access: | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25618 |
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| author | Qiyuan Bai Hao Chen Zhen Gao Xuhua Li Jiapeng Li Shidong Liu Bing Song Cuntao Yu |
| author_facet | Qiyuan Bai Hao Chen Zhen Gao Xuhua Li Jiapeng Li Shidong Liu Bing Song Cuntao Yu |
| author_sort | Qiyuan Bai |
| collection | DOAJ |
| description | Background: The relationship between diabetes and heart failure significantly impacts public health. This study assessed the prognostic nutritional index (PNI) as a predictor of heart failure risk in adult diabetic patients. Methods: An analysis was performed on 1823 diabetic adults using data collected from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2016. Serum albumin levels and lymphocyte counts were combined to calculate the PNI. We used descriptive statistics categorized by PNI quartiles and performed multivariate logistic regression to adjust for variables including age, gender, ethnicity, and coexisting medical conditions. Results: The median age (mean ± SD) was 59.942 ± 12.171 years, and the mean value ± SD of the PNI was 52.412 ± 5.430. The prevalence of heart failure was 7.405%. In the fully adjusted model, for each 1-unit increase in PNI, the risk of heart failure decreased by 8.2% (odds ratio (OR), 0.918; 95% confidence interval (CI) 0.884, 0.953). Participants in the highest PNI quartile (Q4) had a 63% reduced risk of heart failure compared to those in the lowest quartile (Q1). Tests for interactions did not reveal any statistically significant differences among these stratified subgroups (p for interaction > 0.05). Conclusions: This study demonstrated that a higher PNI was significantly associated with a decreased prevalence of heart failure in adults with diabetes. |
| format | Article |
| id | doaj-art-1e8608d7426a42688b18a7207527f5f2 |
| institution | Kabale University |
| issn | 1530-6550 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj-art-1e8608d7426a42688b18a7207527f5f22025-01-25T10:41:20ZengIMR PressReviews in Cardiovascular Medicine1530-65502025-01-012612561810.31083/RCM25618S1530-6550(24)01599-0Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016)Qiyuan Bai0Hao Chen1Zhen Gao2Xuhua Li3Jiapeng Li4Shidong Liu5Bing Song6Cuntao Yu7The First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaThe First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaDepartment of Cardiac Surgery, Capital Medical University Affiliated Beijing Anzhen Hospital, Beijing Institute of Heart Lung and Blood Vessel Diseases, 100029 Beijing, ChinaThe First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaDepartment of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 200233 Shanghai, ChinaThe First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaThe First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaThe First Clinical Medical College of Lanzhou University, 730000 Lanzhou, Gansu, ChinaBackground: The relationship between diabetes and heart failure significantly impacts public health. This study assessed the prognostic nutritional index (PNI) as a predictor of heart failure risk in adult diabetic patients. Methods: An analysis was performed on 1823 diabetic adults using data collected from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2016. Serum albumin levels and lymphocyte counts were combined to calculate the PNI. We used descriptive statistics categorized by PNI quartiles and performed multivariate logistic regression to adjust for variables including age, gender, ethnicity, and coexisting medical conditions. Results: The median age (mean ± SD) was 59.942 ± 12.171 years, and the mean value ± SD of the PNI was 52.412 ± 5.430. The prevalence of heart failure was 7.405%. In the fully adjusted model, for each 1-unit increase in PNI, the risk of heart failure decreased by 8.2% (odds ratio (OR), 0.918; 95% confidence interval (CI) 0.884, 0.953). Participants in the highest PNI quartile (Q4) had a 63% reduced risk of heart failure compared to those in the lowest quartile (Q1). Tests for interactions did not reveal any statistically significant differences among these stratified subgroups (p for interaction > 0.05). Conclusions: This study demonstrated that a higher PNI was significantly associated with a decreased prevalence of heart failure in adults with diabetes.https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25618prognostic nutritional indexdiabetesheart failurenhanes |
| spellingShingle | Qiyuan Bai Hao Chen Zhen Gao Xuhua Li Jiapeng Li Shidong Liu Bing Song Cuntao Yu Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) Reviews in Cardiovascular Medicine prognostic nutritional index diabetes heart failure nhanes |
| title | Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) |
| title_full | Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) |
| title_fullStr | Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) |
| title_full_unstemmed | Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) |
| title_short | Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) |
| title_sort | correlation between prognostic nutritional index and heart failure in adults with diabetes in the united states study results from nhanes 1999 2016 |
| topic | prognostic nutritional index diabetes heart failure nhanes |
| url | https://www.imrpress.com/journal/RCM/26/1/10.31083/RCM25618 |
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