Chemotherapeutic hormesis induced by the tumor microenvironment in refractory ovarian cancer

Chemotherapeutic hormesis induced by the tumor microenvironment in refractory ovarian cancer

Abstract Advanced ovarian cancer often presents with multiple lesions exhibiting varying responses to chemotherapy, highlighting the critical influence of the tumor microenvironment (TME). This study investigates the phenomenon of chemotherapeutic hormesis, wherein low doses of chemotherapeutic agen...

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Bibliographic Details
Main Authors: Xuboya Chang, Satoshi Tamauchi, Atsushi Nakagawa, Wang Xinyuan, Kosuke Yoshida, Akira Yokoi, Nobuhisa Yoshikawa, Hiroaki Kajiyama
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Ovarian cancer
Chemotherapy
Tumor microenvironment
Hormesis
Glutathione
Online Access:https://doi.org/10.1038/s41598-024-84290-7
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https://doi.org/10.1038/s41598-024-84290-7

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