Clear cell adenocarcinoma of the male urethra: clinical case report

Primary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no data about the mo...

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Bibliographic Details
Main Authors: Juliana Sinezio Santos, Gabriella Oliveira Mendes, Fernando Sabino Marques Monteiro
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2021-10-01
Series:Brazilian Journal of Oncology
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Online Access:http://www.brazilianjournalofoncology.com.br/details/149/en-US/clear-cell-adenocarcinoma-of-the-male-urethra--clinical-case-report
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Summary:Primary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no data about the most appropriate treatment for this disease. We aim to describe a clinical case of primary clear cell adenocarcinoma of the urethra in a young male patient. This is a 36-year-old male diagnosed with primary clear cell adenocarcinoma of the urethra whom underwent a surgery for localized disease and about 30 months later he had a local and systemic recurrence. He was treated with platinum-based chemotherapy and presented an excellent clinical and radiological response. Although there is no optimal treatment for this malignancy, in the case of metastatic disease, systemic platinum-based chemotherapy should be considered an appropriate option.
ISSN:2526-8732