The Validation of Antibodies Suitable for Flow Cytometric Analysis and Immunopeptidomics of Peptide–MHC Complexes in the Outbred Swiss Albino Mouse Strain

The Validation of Antibodies Suitable for Flow Cytometric Analysis and Immunopeptidomics of Peptide–MHC Complexes in the Outbred Swiss Albino Mouse Strain

Antigen presentation on major histocompatibility complex (MHC) molecules is central to the initiation of immune responses, and a lot of our understanding about the antigen processing and presentation pathway has been gained through studies in mice. MHC molecules are the most genetically diverse gene...

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Bibliographic Details
Main Authors: Shanzou Chung, Isambard G. Knox-Johnson, Sarah E. Gazzard, Runqiu Song, Ngoc H. Le, Luise A. Cullen-McEwen, John F. Bertram, Anthony W. Purcell, Asolina Braun
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Methods and Protocols
Subjects:
Swiss mice
antigen presentation
immunopeptidomics
major histocompatibility complex
MHC ligands
flow cytometry
Online Access:https://www.mdpi.com/2409-9279/8/3/43
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