Antioxidant, anti-inflammatory, and anti-diabetic assessment of (2Z)-2(arylimino)-2Hchromene-3-carboxamides: An in vitro-in silico study by applying ANN-GA, MCDM, and RSM optimization techniques

Antioxidant, anti-inflammatory, and anti-diabetic assessment of (2Z)-2(arylimino)-2Hchromene-3-carboxamides: An in vitro-in silico study by applying ANN-GA, MCDM, and RSM optimization techniques

This study investigates four novel iminocoumarin derivatives (3–6), previously synthesized and characterized, for their antioxidant, anti-inflammatory, and antidiabetic properties at different concentrations (12.5, 25, 50, 100, 200, 400, 800, and 1600 g/mL). Artificial neural network (ANN) approache...

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Bibliographic Details
Main Authors: Wassila Saiah, Amal Rabahi, Messaouda Boumaaza, Mostefa Hani, Ahmed Belaadi, Yazid Chetbani, Hamza Saidi, Aissa Laouissi, Djamel Ghernaout, Muhammad Imam Ammarullah, Elhadj-Ahmed Koceir
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Results in Chemistry
Subjects:
Iminocoumarin
Antioxidant
Response surface methodology
Anti-inflammatory
Antidiabetic
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625002322
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