Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial

Background. There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program...

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Main Authors: R. Casañas, R. Catalán, R. Penadés, J. Real, S. Valero, MA. Muñoz, LL. Lalucat-Jo, M. Casas
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/718607
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author R. Casañas
R. Catalán
R. Penadés
J. Real
S. Valero
MA. Muñoz
LL. Lalucat-Jo
M. Casas
author_facet R. Casañas
R. Catalán
R. Penadés
J. Real
S. Valero
MA. Muñoz
LL. Lalucat-Jo
M. Casas
author_sort R. Casañas
collection DOAJ
description Background. There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention. Methods. 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis. Results. The PE program group showed remission of symptoms of 40% (P=0.001) posttreatment and 42% (P=0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P=0.008; effect size Cohen’s d′=0.55). Conclusions. The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.
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spelling doaj-art-1dd0e69f88e44d2fa69ba36d5c1682982025-02-03T05:50:25ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/718607718607Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled TrialR. Casañas0R. Catalán1R. Penadés2J. Real3S. Valero4MA. Muñoz5LL. Lalucat-Jo6M. Casas7Research Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, SpainClinical Institute of Neurosciences (ICN), Hospital Clinic, Barcelona, SpainClinical Institute of Neurosciences (ICN), Hospital Clinic, Barcelona, SpainPrimary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, SpainPrimary Healthcare University Research Institute IDIAP-Jordi Gol, Institut Català de la Salut (ICS), C/Sardenya 375, 08036 Barcelona, SpainResearch Department, Centre Higiene Mental (CHM) Les Corts, C/Numancia, 103-105 Bajos, 08029 Barcelona, SpainCentro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Madrid, SpainBackground. There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention. Methods. 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis. Results. The PE program group showed remission of symptoms of 40% (P=0.001) posttreatment and 42% (P=0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P=0.008; effect size Cohen’s d′=0.55). Conclusions. The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.http://dx.doi.org/10.1155/2015/718607
spellingShingle R. Casañas
R. Catalán
R. Penadés
J. Real
S. Valero
MA. Muñoz
LL. Lalucat-Jo
M. Casas
Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
The Scientific World Journal
title Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
title_full Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
title_fullStr Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
title_full_unstemmed Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
title_short Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial
title_sort evaluation of the effectiveness of a psychoeducational intervention in treatment naive patients with antidepressant medication in primary care a randomized controlled trial
url http://dx.doi.org/10.1155/2015/718607
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