Treatment effect of intravenous high-dose selenium in sepsis phenotypes: a retrospective analysis of a large multicenter randomized controlled trial

Abstract Background Treatment effect of high-dose intravenous selenium remains controversial in patients with sepsis or septic shock. Here, we reanalyzed data from the randomized placebo-controlled trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (SISPCT) to r...

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Main Authors: David I. Radke, Holger Bogatsch, Christoph Engel, Frank Bloos, Patrick Meybohm, Michael Bauer, Anna Lulu Homayr, Christian Stoppe, Gunnar Elke, Matthias Lindner, the SepNet Critical Care Trials Group
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Intensive Care
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Online Access:https://doi.org/10.1186/s40560-025-00790-2
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