Treatments for Severe Cutaneous Adverse Reactions
Severe cutaneous adverse reaction (SCAR) is life-threatening. It consists of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/1503709 |
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| _version_ | 1832554269043064832 |
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| author | Yung-Tsu Cho Chia-Yu Chu |
| author_facet | Yung-Tsu Cho Chia-Yu Chu |
| author_sort | Yung-Tsu Cho |
| collection | DOAJ |
| description | Severe cutaneous adverse reaction (SCAR) is life-threatening. It consists of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE). In the past years, emerging studies have provided better understandings regarding the pathogenesis of these diseases. These diseases have unique presentations and distinct pathomechanisms. Therefore, theoretically, the options of treatments might be different among various SCARs. However, due to the rarity of these diseases, sufficient evidence is still lacking to support the best choice of treatment for patients with SCAR. Herein, we will provide a concise review with an emphasis on the characteristics and treatments of each SCAR. It may serve as a guidance based on the current best of knowledge and may shed light on the directions for further investigations. |
| format | Article |
| id | doaj-art-1d96004146aa4f8b85f405568e6db93f |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-1d96004146aa4f8b85f405568e6db93f2025-02-03T05:51:49ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/15037091503709Treatments for Severe Cutaneous Adverse ReactionsYung-Tsu Cho0Chia-Yu Chu1Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanDepartment of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, TaiwanSevere cutaneous adverse reaction (SCAR) is life-threatening. It consists of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalized exanthematous pustulosis (AGEP), and generalized bullous fixed drug eruptions (GBFDE). In the past years, emerging studies have provided better understandings regarding the pathogenesis of these diseases. These diseases have unique presentations and distinct pathomechanisms. Therefore, theoretically, the options of treatments might be different among various SCARs. However, due to the rarity of these diseases, sufficient evidence is still lacking to support the best choice of treatment for patients with SCAR. Herein, we will provide a concise review with an emphasis on the characteristics and treatments of each SCAR. It may serve as a guidance based on the current best of knowledge and may shed light on the directions for further investigations.http://dx.doi.org/10.1155/2017/1503709 |
| spellingShingle | Yung-Tsu Cho Chia-Yu Chu Treatments for Severe Cutaneous Adverse Reactions Journal of Immunology Research |
| title | Treatments for Severe Cutaneous Adverse Reactions |
| title_full | Treatments for Severe Cutaneous Adverse Reactions |
| title_fullStr | Treatments for Severe Cutaneous Adverse Reactions |
| title_full_unstemmed | Treatments for Severe Cutaneous Adverse Reactions |
| title_short | Treatments for Severe Cutaneous Adverse Reactions |
| title_sort | treatments for severe cutaneous adverse reactions |
| url | http://dx.doi.org/10.1155/2017/1503709 |
| work_keys_str_mv | AT yungtsucho treatmentsforseverecutaneousadversereactions AT chiayuchu treatmentsforseverecutaneousadversereactions |