Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy

Herein we describe the case of an elderly diabetic gentleman presenting with a two-week history of dyspnea and nonproductive cough, found to have a large left anterolateral chest wall mass. Further characterization through computed tomography (CT) of the chest revealed a soft tissue mass in the left...

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Main Authors: Joseph Allencherril, Sebastian Bruera, Ronan Allencherril, Richard J. Hamill
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/3531823
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author Joseph Allencherril
Sebastian Bruera
Ronan Allencherril
Richard J. Hamill
author_facet Joseph Allencherril
Sebastian Bruera
Ronan Allencherril
Richard J. Hamill
author_sort Joseph Allencherril
collection DOAJ
description Herein we describe the case of an elderly diabetic gentleman presenting with a two-week history of dyspnea and nonproductive cough, found to have a large left anterolateral chest wall mass. Further characterization through computed tomography (CT) of the chest revealed a soft tissue mass in the left anterior lower hemithorax found to be hepatocellular carcinoma (HCC). The liver, spleen, and pancreas were unremarkable. Diagnostic labs were unremarkable. The patient had no history of hepatitis, alcohol abuse, or illicit substance use. Pathological examination and immunohistochemical staining of the chest mass biopsy were consistent with metastatic hepatocellular carcinoma (HCC). The patient opted to pursue no further medical intervention and expired two weeks later. To the authors’ knowledge, this is one of very few descriptions of isolated hepatocellular carcinoma found in the absence of a primary liver lesion and classical risk factors for hepatocarcinogenesis. This case highlights that HCC may present independently of liver lesions seen on imaging in a patient without clear signs or symptoms of liver. HCC should be considered in cases of isolated tumors with unclear primaries as ectopic carcinogenesis and occult primary malignancy are possibilities.
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spelling doaj-art-1d7fd63c4cdd49b1939e04d1161fa5ba2025-02-03T06:07:07ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/35318233531823Lone Hepatocellular Carcinoma: An Isolated Chest Wall MalignancyJoseph Allencherril0Sebastian Bruera1Ronan Allencherril2Richard J. Hamill3Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USADepartment of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USAUniversity of Texas Medical Branch, Galveston, TX, USADepartment of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX, USAHerein we describe the case of an elderly diabetic gentleman presenting with a two-week history of dyspnea and nonproductive cough, found to have a large left anterolateral chest wall mass. Further characterization through computed tomography (CT) of the chest revealed a soft tissue mass in the left anterior lower hemithorax found to be hepatocellular carcinoma (HCC). The liver, spleen, and pancreas were unremarkable. Diagnostic labs were unremarkable. The patient had no history of hepatitis, alcohol abuse, or illicit substance use. Pathological examination and immunohistochemical staining of the chest mass biopsy were consistent with metastatic hepatocellular carcinoma (HCC). The patient opted to pursue no further medical intervention and expired two weeks later. To the authors’ knowledge, this is one of very few descriptions of isolated hepatocellular carcinoma found in the absence of a primary liver lesion and classical risk factors for hepatocarcinogenesis. This case highlights that HCC may present independently of liver lesions seen on imaging in a patient without clear signs or symptoms of liver. HCC should be considered in cases of isolated tumors with unclear primaries as ectopic carcinogenesis and occult primary malignancy are possibilities.http://dx.doi.org/10.1155/2017/3531823
spellingShingle Joseph Allencherril
Sebastian Bruera
Ronan Allencherril
Richard J. Hamill
Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
Case Reports in Medicine
title Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
title_full Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
title_fullStr Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
title_full_unstemmed Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
title_short Lone Hepatocellular Carcinoma: An Isolated Chest Wall Malignancy
title_sort lone hepatocellular carcinoma an isolated chest wall malignancy
url http://dx.doi.org/10.1155/2017/3531823
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AT sebastianbruera lonehepatocellularcarcinomaanisolatedchestwallmalignancy
AT ronanallencherril lonehepatocellularcarcinomaanisolatedchestwallmalignancy
AT richardjhamill lonehepatocellularcarcinomaanisolatedchestwallmalignancy