Establishment of an animal model of immune‐related adverse events induced by immune checkpoint inhibitors

Establishment of an animal model of immune‐related adverse events induced by immune checkpoint inhibitors

Abstract Objective Immunotherapy, specifically immune checkpoint inhibitors (ICIs), has revolutionized cancer treatment. However, it can also cause immune‐related adverse events (irAEs). This study aimed to develop a clinically practical animal model of irAEs using BALB/c mice. Methods Subcutaneous...

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Bibliographic Details
Main Authors: Yuan Meng, Yingge Lv, Meng Shen, Wenwen Yu, Yumeng Liu, Ting Liu, Gen Liu, Shiya Ma, Zhenzhen Hui, Xiubao Ren, Liang Liu
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Cancer Medicine
Subjects:
animal model
cancer immunotherapy
immune checkpoint inhibitors
immune‐related adverse events
Online Access:https://doi.org/10.1002/cam4.70011
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https://doi.org/10.1002/cam4.70011

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