B7‐H3 promotes nasopharyngeal carcinoma progression by regulating CD8+ T cell exhaustion

B7‐H3 promotes nasopharyngeal carcinoma progression by regulating CD8+ T cell exhaustion

Abstract Background B7‐H3 protein is an important regulator of the adaptive immune response in human tumorigenesis. 4‐1BB is a co‐stimulatory receptor expressed on activated CD8+ T cells, and regulates T cell immunity. Here, we investigated the role of B7‐H3 in the growth and invasion of nasopharyng...

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Bibliographic Details
Main Authors: Zhaoen Ma, Gui Chen, Hao Li, Saixuan Yang, Yali Xu, Bolin Pan, Wuping Lai, Guangui Chen, Wenjing Liao, Xiaowen Zhang
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Immunity, Inflammation and Disease
Subjects:
4‐1BB
B7‐H3
CD8+ T
nasopharyngeal carcinoma
tumor immunity
Online Access:https://doi.org/10.1002/iid3.70005
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