Crocin Alleviates Hippocampal Neuron Injury in Rats with Cerebral Ischemia-Reperfusion by Inhibiting JAK2/STAT3 Signaling Pathway

Crocin Alleviates Hippocampal Neuron Injury in Rats with Cerebral Ischemia-Reperfusion by Inhibiting JAK2/STAT3 Signaling Pathway

ObjectiveTo investigate the effect of Crocin (CRO) on rats with hippocampal neuron cerebral ischemia reperfusion (CI/R) injury and explore its potential mechanism.MethodsA total of 144 male SD rats were selected and randomly divided into sham group, model (CI/R) group, CRO low-, medium-, high-dose (...

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Bibliographic Details
Main Authors: LI Xiaolei, ZHU Haisheng, MA Ruijuan, YAO Li, HU Ke, FENG Lina, WANG Xudong
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2024-06-01
Series:康复学报
Subjects:
cerebral ischemia-reperfusion
crocin
Hippocampal neuron
JAK2/STAT3 signaling pathway
inflammation
apoptosis
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2024.03005
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