Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia

The skeletal system is a frequent site for metastases of urothelial carcinoma (UC) of the bladder (22–37%). Of those cases involving bone, the marrow is infiltrated in 27% of patients. Imaging modalities, such as X-ray and CT, will detect gross skeletal lesions in the vast majority of these patients...

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Main Authors: Robert C. Chan, Greg L. Hundemer, Amy Tatsas, Michael S. Cookson
Format: Article
Language:English
Published: Wiley 2007-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2007.168
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author Robert C. Chan
Greg L. Hundemer
Amy Tatsas
Michael S. Cookson
author_facet Robert C. Chan
Greg L. Hundemer
Amy Tatsas
Michael S. Cookson
author_sort Robert C. Chan
collection DOAJ
description The skeletal system is a frequent site for metastases of urothelial carcinoma (UC) of the bladder (22–37%). Of those cases involving bone, the marrow is infiltrated in 27% of patients. Imaging modalities, such as X-ray and CT, will detect gross skeletal lesions in the vast majority of these patients with bone marrow involvement, however, most patients with bone involvement are symptomatic at presentation. Additionally, there have been few reports in the literature of bone marrow metastases from UC presenting with isolated thrombocytopenia.
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spelling doaj-art-1d1e698d41df4e109b00a73e93ca68ca2025-02-03T05:50:43ZengWileyThe Scientific World Journal1537-744X2007-01-0171000100310.1100/tsw.2007.168Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated ThrombocytopeniaRobert C. Chan0Greg L. Hundemer1Amy Tatsas2Michael S. Cookson3Department of Urology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Urology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Pathology, Vanderbilt University Medical Center, Nashville, TN, USADepartment of Urology, Vanderbilt University Medical Center, Nashville, TN, USAThe skeletal system is a frequent site for metastases of urothelial carcinoma (UC) of the bladder (22–37%). Of those cases involving bone, the marrow is infiltrated in 27% of patients. Imaging modalities, such as X-ray and CT, will detect gross skeletal lesions in the vast majority of these patients with bone marrow involvement, however, most patients with bone involvement are symptomatic at presentation. Additionally, there have been few reports in the literature of bone marrow metastases from UC presenting with isolated thrombocytopenia.http://dx.doi.org/10.1100/tsw.2007.168
spellingShingle Robert C. Chan
Greg L. Hundemer
Amy Tatsas
Michael S. Cookson
Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
The Scientific World Journal
title Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
title_full Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
title_fullStr Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
title_full_unstemmed Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
title_short Urothelial Carcinoma of the Bladder Metastatic to Bone Marrow Presenting as Isolated Thrombocytopenia
title_sort urothelial carcinoma of the bladder metastatic to bone marrow presenting as isolated thrombocytopenia
url http://dx.doi.org/10.1100/tsw.2007.168
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AT amytatsas urothelialcarcinomaofthebladdermetastatictobonemarrowpresentingasisolatedthrombocytopenia
AT michaelscookson urothelialcarcinomaofthebladdermetastatictobonemarrowpresentingasisolatedthrombocytopenia