Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns
Treatment of burns such as using toothpaste, butter, oil, and ice is less effective in treating burns. A safer and more effective alternative is needed as a dressing for burn wounds. The use of burn wound coverings with the moist wound healing principle is recommended because they are flexible, elas...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2025-01-01
|
| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_04011.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832098388453097472 |
|---|---|
| author | Winda Puji Lestari Roro Khorinnisa Hayatul Nurtiara Alma Lita Septiana Enggel Yuliyanti Dwi Nur Handayani Santi |
| author_facet | Winda Puji Lestari Roro Khorinnisa Hayatul Nurtiara Alma Lita Septiana Enggel Yuliyanti Dwi Nur Handayani Santi |
| author_sort | Winda Puji Lestari Roro |
| collection | DOAJ |
| description | Treatment of burns such as using toothpaste, butter, oil, and ice is less effective in treating burns. A safer and more effective alternative is needed as a dressing for burn wounds. The use of burn wound coverings with the moist wound healing principle is recommended because they are flexible, elastic, and support the burn wound healing process. Patikan kebo leaves contain flavonoids, tannins, alkaloids, saponins, and terpenoids which function as antibacterial and anti-inflammatory in the healing process of second-degree burns. This research aims to make a hydrogel from patikan kebo leaf extract with honey and tests its antibacterial and anti-inflammatory effectiveness as a treatment for second-degree burns. The method used is synthesis hydrogel, antibacterial and anti-inflammatory tests, and continued testing using histopathology tests. The antibacterial test results showed that the extract didn’t show better activity than the positive control on
Escherichia coli bacteria, while the F4 sample showed the best antibacterial effect on
Streptococcus aureus bacteria. Anti-inflammatory and burn healing test seen from the results of histopathology tests produced the best percentage of burn wound healing in sample F4. |
| format | Article |
| id | doaj-art-1cc886ec68bd4ffebba77d38cafd1762 |
| institution | Kabale University |
| issn | 2267-1242 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj-art-1cc886ec68bd4ffebba77d38cafd17622025-02-05T10:49:56ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016090401110.1051/e3sconf/202560904011e3sconf_icma-sure2024_04011Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree BurnsWinda Puji Lestari Roro0Khorinnisa Hayatul1Nurtiara Alma2Lita Septiana Enggel3Yuliyanti Dwi4Nur Handayani Santi5Departement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanDepartement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanDepartement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanDepartement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanDepartement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanDepartement of Chemistry, Math and Sciences Faculty, Universitas Jenderal SoedirmanTreatment of burns such as using toothpaste, butter, oil, and ice is less effective in treating burns. A safer and more effective alternative is needed as a dressing for burn wounds. The use of burn wound coverings with the moist wound healing principle is recommended because they are flexible, elastic, and support the burn wound healing process. Patikan kebo leaves contain flavonoids, tannins, alkaloids, saponins, and terpenoids which function as antibacterial and anti-inflammatory in the healing process of second-degree burns. This research aims to make a hydrogel from patikan kebo leaf extract with honey and tests its antibacterial and anti-inflammatory effectiveness as a treatment for second-degree burns. The method used is synthesis hydrogel, antibacterial and anti-inflammatory tests, and continued testing using histopathology tests. The antibacterial test results showed that the extract didn’t show better activity than the positive control on Escherichia coli bacteria, while the F4 sample showed the best antibacterial effect on Streptococcus aureus bacteria. Anti-inflammatory and burn healing test seen from the results of histopathology tests produced the best percentage of burn wound healing in sample F4.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_04011.pdf |
| spellingShingle | Winda Puji Lestari Roro Khorinnisa Hayatul Nurtiara Alma Lita Septiana Enggel Yuliyanti Dwi Nur Handayani Santi Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns E3S Web of Conferences |
| title | Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns |
| title_full | Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns |
| title_fullStr | Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns |
| title_full_unstemmed | Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns |
| title_short | Analysis of the Effectiveness of Hydrogel Based on Patikan Kebo Leaf Extract and Honey in Therapy of II Degree Burns |
| title_sort | analysis of the effectiveness of hydrogel based on patikan kebo leaf extract and honey in therapy of ii degree burns |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_04011.pdf |
| work_keys_str_mv | AT windapujilestariroro analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns AT khorinnisahayatul analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns AT nurtiaraalma analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns AT litaseptianaenggel analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns AT yuliyantidwi analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns AT nurhandayanisanti analysisoftheeffectivenessofhydrogelbasedonpatikankeboleafextractandhoneyintherapyofiidegreeburns |