Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study
This study aimed to evaluate the impact of periodic neck ultrasonography (US) on postoperative surveillance for locoregional disease control of patients with low- and intermediate-risk papillary thyroid carcinoma (PTC) who underwent total thyroidectomy. This retrospective cohort study included patie...
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The Japan Endocrine Society
2024-12-01
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| Series: | Endocrine Journal |
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| Online Access: | https://www.jstage.jst.go.jp/article/endocrj/71/12/71_EJ24-0194/_html/-char/en |
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| author | Takahiro Inaishi Dai Takeuchi Takahiro Ichikawa Gai Inaguma Atsushi Hashizume Masaki Okazaki Norikazu Masuda Toyone Kikumori |
| author_facet | Takahiro Inaishi Dai Takeuchi Takahiro Ichikawa Gai Inaguma Atsushi Hashizume Masaki Okazaki Norikazu Masuda Toyone Kikumori |
| author_sort | Takahiro Inaishi |
| collection | DOAJ |
| description | This study aimed to evaluate the impact of periodic neck ultrasonography (US) on postoperative surveillance for locoregional disease control of patients with low- and intermediate-risk papillary thyroid carcinoma (PTC) who underwent total thyroidectomy. This retrospective cohort study included patients with PTC who underwent total thyroidectomy and central neck dissection at our institution between January, 2000 and December, 2016. The patients were divided into two groups: the physical examination (PE) group (follow-up by PE without periodic US) and the US group (follow-up by PE with periodic US). Serum thyroglobulin levels were measured periodically in both groups. Propensity score matching was used to rigorously balance the significant variables and assess the 10-year postoperative outcomes between the groups. Of the 189 patients, 150 were included after matching (75 in each group). There were no significant differences between the two groups in terms of background characteristics. The median follow-up period was 127.9 months. There was no significant difference in locoregional relapse-free survival between the PE and US groups (97.0 vs. 98.7%, p = 0.541). The overall survival was 96.7% and 98.7% in the PE and US groups, respectively, with no significant difference (p = 0.364). This study demonstrated that the addition of periodic US to PE for postoperative surveillance of patients with low- and intermediate-risk PTC who underwent total thyroidectomy did not significantly affect locoregional control. |
| format | Article |
| id | doaj-art-1cc0454a9e304c17af3fbbd7cfdfc921 |
| institution | Kabale University |
| issn | 1348-4540 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | The Japan Endocrine Society |
| record_format | Article |
| series | Endocrine Journal |
| spelling | doaj-art-1cc0454a9e304c17af3fbbd7cfdfc9212025-01-22T05:34:07ZengThe Japan Endocrine SocietyEndocrine Journal1348-45402024-12-0171121135114310.1507/endocrj.EJ24-0194endocrjImpact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched studyTakahiro Inaishi0Dai Takeuchi1Takahiro Ichikawa2Gai Inaguma3Atsushi Hashizume4Masaki Okazaki5Norikazu Masuda6Toyone Kikumori7Department of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Clinical Research Education, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Clinical Research Education, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanDepartment of Breast and Endocrine Surgery, Nagoya University Graduate School of Medicine, Nagoya 466-8550, JapanThis study aimed to evaluate the impact of periodic neck ultrasonography (US) on postoperative surveillance for locoregional disease control of patients with low- and intermediate-risk papillary thyroid carcinoma (PTC) who underwent total thyroidectomy. This retrospective cohort study included patients with PTC who underwent total thyroidectomy and central neck dissection at our institution between January, 2000 and December, 2016. The patients were divided into two groups: the physical examination (PE) group (follow-up by PE without periodic US) and the US group (follow-up by PE with periodic US). Serum thyroglobulin levels were measured periodically in both groups. Propensity score matching was used to rigorously balance the significant variables and assess the 10-year postoperative outcomes between the groups. Of the 189 patients, 150 were included after matching (75 in each group). There were no significant differences between the two groups in terms of background characteristics. The median follow-up period was 127.9 months. There was no significant difference in locoregional relapse-free survival between the PE and US groups (97.0 vs. 98.7%, p = 0.541). The overall survival was 96.7% and 98.7% in the PE and US groups, respectively, with no significant difference (p = 0.364). This study demonstrated that the addition of periodic US to PE for postoperative surveillance of patients with low- and intermediate-risk PTC who underwent total thyroidectomy did not significantly affect locoregional control.https://www.jstage.jst.go.jp/article/endocrj/71/12/71_EJ24-0194/_html/-char/enlocoregional recurrencepapillary thyroid carcinomasurveillancetotal thyroidectomyultrasonography |
| spellingShingle | Takahiro Inaishi Dai Takeuchi Takahiro Ichikawa Gai Inaguma Atsushi Hashizume Masaki Okazaki Norikazu Masuda Toyone Kikumori Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study Endocrine Journal locoregional recurrence papillary thyroid carcinoma surveillance total thyroidectomy ultrasonography |
| title | Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study |
| title_full | Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study |
| title_fullStr | Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study |
| title_full_unstemmed | Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study |
| title_short | Impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low- and intermediate-risk papillary thyroid carcinoma: a propensity score-matched study |
| title_sort | impact of periodic neck ultrasonography on locoregional disease control in surveillance after total thyroidectomy for patients with low and intermediate risk papillary thyroid carcinoma a propensity score matched study |
| topic | locoregional recurrence papillary thyroid carcinoma surveillance total thyroidectomy ultrasonography |
| url | https://www.jstage.jst.go.jp/article/endocrj/71/12/71_EJ24-0194/_html/-char/en |
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