Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana

Most mortality studies usually attribute death to single disease, while various other diseases could also act in the same individual or a population at large. Few works have been done by considering HIV, Tuberculosis (TB), and Hepatitis B (HB) as jointly acting in a population in spite of their high...

Full description

Saved in:
Bibliographic Details
Main Authors: Clement Twumasi, Louis Asiedu, Ezekiel N. N. Nortey
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2019/2697618
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832560790849191936
author Clement Twumasi
Louis Asiedu
Ezekiel N. N. Nortey
author_facet Clement Twumasi
Louis Asiedu
Ezekiel N. N. Nortey
author_sort Clement Twumasi
collection DOAJ
description Most mortality studies usually attribute death to single disease, while various other diseases could also act in the same individual or a population at large. Few works have been done by considering HIV, Tuberculosis (TB), and Hepatitis B (HB) as jointly acting in a population in spite of their high rate of infections in Ghana. This study applied competing risk methods on these three diseases by assuming they were the major risks in the study population. Among all opportunistic infections that could also act within HIV-infected individuals, TB has been asserted to be the most predominant. Other studies have also shown cases of HIV and Hepatitis B coinfections. The validity of these comorbidity assertions was statistically determined by exploring the conditional dependencies existing among HIV, TB, and HB through Bayesian networks or directed graphical model. Through Classification tree, sex and age group of individuals were found as significant demographic predictors that influence the prevalence of HIV and TB. Females were more likely to contract HIV, whereas males were prone to contracting TB.
format Article
id doaj-art-1c90a36d441a4b22aa50c7c30b35017f
institution Kabale University
issn 1712-9532
1918-1493
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-1c90a36d441a4b22aa50c7c30b35017f2025-02-03T01:26:41ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932019-01-01201910.1155/2019/26976182697618Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in GhanaClement Twumasi0Louis Asiedu1Ezekiel N. N. Nortey2School of Mathematics, Cardiff University, Cardiff, UKDepartment of Statistics & Actuarial Science, School of Physical and Mathematical Sciences, University of Ghana, Legon, Accra, GhanaDepartment of Statistics & Actuarial Science, School of Physical and Mathematical Sciences, University of Ghana, Legon, Accra, GhanaMost mortality studies usually attribute death to single disease, while various other diseases could also act in the same individual or a population at large. Few works have been done by considering HIV, Tuberculosis (TB), and Hepatitis B (HB) as jointly acting in a population in spite of their high rate of infections in Ghana. This study applied competing risk methods on these three diseases by assuming they were the major risks in the study population. Among all opportunistic infections that could also act within HIV-infected individuals, TB has been asserted to be the most predominant. Other studies have also shown cases of HIV and Hepatitis B coinfections. The validity of these comorbidity assertions was statistically determined by exploring the conditional dependencies existing among HIV, TB, and HB through Bayesian networks or directed graphical model. Through Classification tree, sex and age group of individuals were found as significant demographic predictors that influence the prevalence of HIV and TB. Females were more likely to contract HIV, whereas males were prone to contracting TB.http://dx.doi.org/10.1155/2019/2697618
spellingShingle Clement Twumasi
Louis Asiedu
Ezekiel N. N. Nortey
Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
Canadian Journal of Infectious Diseases and Medical Microbiology
title Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
title_full Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
title_fullStr Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
title_full_unstemmed Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
title_short Statistical Modeling of HIV, Tuberculosis, and Hepatitis B Transmission in Ghana
title_sort statistical modeling of hiv tuberculosis and hepatitis b transmission in ghana
url http://dx.doi.org/10.1155/2019/2697618
work_keys_str_mv AT clementtwumasi statisticalmodelingofhivtuberculosisandhepatitisbtransmissioninghana
AT louisasiedu statisticalmodelingofhivtuberculosisandhepatitisbtransmissioninghana
AT ezekielnnnortey statisticalmodelingofhivtuberculosisandhepatitisbtransmissioninghana