Application of Humanized MHC Transgenic Mice in the Screening of HLA–Restricted T Cell Epitopes for Influenza Vaccines

Background: Annual influenza epidemics pose a significant burden on the global healthcare system. The currently available vaccines mainly induce the production of neutralizing antibodies against hemagglutinin and neuraminidase, which are prone to antigenic variation, and this can reduce vaccine effi...

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Bibliographic Details
Main Authors: Yuwei Wei, Keyu Sun, Xuelian Han, Yali Sun, Jiejie Zhang, Yuan Wang, Qi Yin, Tiantian Yang, Kai Yuan, Min Li, Guangyu Zhao
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Vaccines
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Online Access:https://www.mdpi.com/2076-393X/13/3/331
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