Cascade amplification of tumor chemodynamic therapy and starvation with re-educated TAMs via Fe-MOF based functional nanosystem

Cascade amplification of tumor chemodynamic therapy and starvation with re-educated TAMs via Fe-MOF based functional nanosystem

Abstract Tumor microenvironment is characterized by the high concentration of reactive oxygen species (ROS), which is an effective key used to open the Pandora’s Box against cancer. Herein, a tumor-targeted nanosystem HFNP@GOX@PFC composed of ROS-cleaved Fe-based metal–organic framework, hyaluronic...

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Bibliographic Details
Main Authors: Xinmin Zheng, Xiang Li, Siyu Meng, Guolin Shi, Hui Li, Huiping Du, Liangliang Dai, Hui Yang
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Nanobiotechnology
Subjects:
Cascade amplification
Tumor starvation
Chemodynamic therapy
Re-education macrophages
Fe-Mof nanosystem
Online Access:https://doi.org/10.1186/s12951-023-01878-3
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https://doi.org/10.1186/s12951-023-01878-3

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