Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report
Ischemic colitis is a serious drug-induced adverse event. There are only few cases of immunosuppression-associated ischemic colitis described in the literature, but none with a pancolitis-like manifestation. We report the case of a 72-year-old female patient who developed a pancolitis with ischemic...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/698404 |
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| author | A. Dalbeni E. Capoferro L. Bernardoni P. Capelli A. Caliò A. Gabbrielli F. Capra |
| author_facet | A. Dalbeni E. Capoferro L. Bernardoni P. Capelli A. Caliò A. Gabbrielli F. Capra |
| author_sort | A. Dalbeni |
| collection | DOAJ |
| description | Ischemic colitis is a serious drug-induced adverse event. There are only few cases of immunosuppression-associated ischemic colitis described in the literature, but none with a pancolitis-like manifestation. We report the case of a 72-year-old female patient who developed a pancolitis with ischemic injury on immunosuppressive treatment with steroids and azathioprine for autoimmune hepatitis. The patient presented with massive rectal bleeding. Colonoscopy confirmed the diagnosis of pancolitis. The results of histological examination indicated drug-induced ischemic colitis involving the entire colon. This is the first case of ischemic pancolitis mimicking an inflammatory bowel disease (IBD) in a patient with immunosuppressive therapy. |
| format | Article |
| id | doaj-art-1c13145b0a2d47edae75d1bd602d9ed3 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-1c13145b0a2d47edae75d1bd602d9ed32025-02-03T01:11:34ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362012-01-01201210.1155/2012/698404698404Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case ReportA. Dalbeni0E. Capoferro1L. Bernardoni2P. Capelli3A. Caliò4A. Gabbrielli5F. Capra6Section of Internal Medicine, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Gastroenterology, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Endoscopy, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Pathology, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Pathology, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Endoscopy, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalySection of Internal Medicine, Department of Biomedical and Surgical Science, University of Verona, 10-37134 Verona, ItalyIschemic colitis is a serious drug-induced adverse event. There are only few cases of immunosuppression-associated ischemic colitis described in the literature, but none with a pancolitis-like manifestation. We report the case of a 72-year-old female patient who developed a pancolitis with ischemic injury on immunosuppressive treatment with steroids and azathioprine for autoimmune hepatitis. The patient presented with massive rectal bleeding. Colonoscopy confirmed the diagnosis of pancolitis. The results of histological examination indicated drug-induced ischemic colitis involving the entire colon. This is the first case of ischemic pancolitis mimicking an inflammatory bowel disease (IBD) in a patient with immunosuppressive therapy.http://dx.doi.org/10.1155/2012/698404 |
| spellingShingle | A. Dalbeni E. Capoferro L. Bernardoni P. Capelli A. Caliò A. Gabbrielli F. Capra Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report Case Reports in Gastrointestinal Medicine |
| title | Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report |
| title_full | Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report |
| title_fullStr | Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report |
| title_full_unstemmed | Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report |
| title_short | Pancolitis with Ischemic Injury as a Complication of Immunosuppressive Treatment in a Patient with Autoimmune Hepatitis: A Case Report |
| title_sort | pancolitis with ischemic injury as a complication of immunosuppressive treatment in a patient with autoimmune hepatitis a case report |
| url | http://dx.doi.org/10.1155/2012/698404 |
| work_keys_str_mv | AT adalbeni pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT ecapoferro pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT lbernardoni pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT pcapelli pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT acalio pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT agabbrielli pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport AT fcapra pancolitiswithischemicinjuryasacomplicationofimmunosuppressivetreatmentinapatientwithautoimmunehepatitisacasereport |