Vitamin K deficiency bleeding in children with cholestatic liver disease: a systematic review and meta-analysis

Vitamin K deficiency bleeding in children with cholestatic liver disease: a systematic review and meta-analysis

Vitamin K deficiency (VKD) in cholestatic liver disease affects up to 23% of pediatric patients. While several vitamin K (VK) prophylaxis regimens have been proposed, optimal therapeutic strategies remain undefined. The study aimed to identify the most effective VK prophylaxis for children with chol...

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Main Authors: Anusak Sakwit, Pongpak Pongphitcha, Patcharee Komvilaisak, Masayuki Ochiai, Daijiro Takahashi, Shutaro Suga, Ampaiwan Chuansumrit, Marisol Betensky, Stephen P. Pereira, Amber Afzal, C. Heleen van Ommen, Neil Goldenberg, Sasivimol Rattanasiri, Nongnuch Sirachainan
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
cholestatic liver disease
children
vitamin K
prophylaxis
bleeding
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925001712
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