$R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission

In this paper, we study an age-structured SIS epidemic model with periodicity and vertical transmission. We show that the spectral radius of the Fréchet derivative of a nonlinear integral operator plays the role of a threshold value for the global behavior of the model, that is, if the value is less...

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Main Authors: Toshikazu Kuniya, Mimmo Iannelli
Format: Article
Language:English
Published: AIMS Press 2014-02-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.929
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author Toshikazu Kuniya
Mimmo Iannelli
author_facet Toshikazu Kuniya
Mimmo Iannelli
author_sort Toshikazu Kuniya
collection DOAJ
description In this paper, we study an age-structured SIS epidemic model with periodicity and vertical transmission. We show that the spectral radius of the Fréchet derivative of a nonlinear integral operator plays the role of a threshold value for the global behavior of the model, that is, if the value is less than unity, then the disease-free steady state of the model is globally asymptotically stable, while if the value is greater than unity, then the model has a unique globally asymptotically stable endemic (nontrivial) periodic solution. We also show that the value can coincide with the well-know epidemiological threshold value, the basic reproduction number $\mathcal{R}_0$.
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spelling doaj-art-1b86feb638a44d9fbff08697d80748d62025-01-24T02:28:18ZengAIMS PressMathematical Biosciences and Engineering1551-00182014-02-0111492994510.3934/mbe.2014.11.929$R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmissionToshikazu Kuniya0Mimmo Iannelli1Graduate School of Mathematical Sciences, University of Tokyo, 3-8-1 Komaba Meguro-ku, Tokyo 153-8914Dipartimento di Mathematica, Università di Trento, 38050 Povo (Trento)In this paper, we study an age-structured SIS epidemic model with periodicity and vertical transmission. We show that the spectral radius of the Fréchet derivative of a nonlinear integral operator plays the role of a threshold value for the global behavior of the model, that is, if the value is less than unity, then the disease-free steady state of the model is globally asymptotically stable, while if the value is greater than unity, then the model has a unique globally asymptotically stable endemic (nontrivial) periodic solution. We also show that the value can coincide with the well-know epidemiological threshold value, the basic reproduction number $\mathcal{R}_0$.https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.929periodicityage-structurevertical transmissionbasic reproduction number.sis epidemic model
spellingShingle Toshikazu Kuniya
Mimmo Iannelli
$R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
Mathematical Biosciences and Engineering
periodicity
age-structure
vertical transmission
basic reproduction number.
sis epidemic model
title $R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
title_full $R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
title_fullStr $R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
title_full_unstemmed $R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
title_short $R_0$ and the global behavior of an age-structured SIS epidemic model with periodicity and vertical transmission
title_sort r 0 and the global behavior of an age structured sis epidemic model with periodicity and vertical transmission
topic periodicity
age-structure
vertical transmission
basic reproduction number.
sis epidemic model
url https://www.aimspress.com/article/doi/10.3934/mbe.2014.11.929
work_keys_str_mv AT toshikazukuniya r0andtheglobalbehaviorofanagestructuredsisepidemicmodelwithperiodicityandverticaltransmission
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