Characterization of Glycoprotein 5-Specific Response in Pigs Vaccinated with Modified Live Porcine Reproductive and Respiratory Syndrome Virus Vaccine Derived from Two Different Lineages

Characterization of Glycoprotein 5-Specific Response in Pigs Vaccinated with Modified Live Porcine Reproductive and Respiratory Syndrome Virus Vaccine Derived from Two Different Lineages

Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) is classified into various lineages based on the phylogenetic variation of <i>orf5</i>, which encodes a major surface glycoprotein GP5 containing both neutralizing and non-neutralizing linear epitopes. Sev...

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Bibliographic Details
Main Authors: Jing Huang, Venkatramana D. Krishna, Igor A. D. Paploski, Kimberly VanderWaal, Declan C. Schroeder, Maxim C.-J. Cheeran
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
Subjects:
porcine reproductive and respiratory syndrome virus
glycoprotein 5
neutralization
modified live virus vaccine
epitope
Online Access:https://www.mdpi.com/2076-393X/13/3/247
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