The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus.

Alveolar macrophages represent a first-line innate host defense mechanism for clearing inhaled Aspergillus fumigatus from the lungs, yet contradictory data exist as to which alveolar macrophage recognition receptor is critical for innate immunity to A. fumigatus. Acknowledging that the A. fumigatus...

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Bibliographic Details
Main Authors: Chad Steele, Rekha R Rapaka, Allison Metz, Shannon M Pop, David L Williams, Siamon Gordon, Jay K Kolls, Gordon D Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0010042&type=printable
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