The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients

The Development and Validation of a Simple HPLC-UV Method for the Determination of Vancomycin Concentration in Human Plasma and Application in Critically Ill Patients

Vancomycin is an antimicrobial agent that exhibits high efficacy against Gram-positive bacteria. The importance of therapeutic drug monitoring (TDM) for vancomycin has been substantiated in specific patient cohorts, underscoring the significance of determining vancomycin plasma levels. This study pr...

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Bibliographic Details
Main Authors: Asma Aboelezz, Novel Solomon Tesfamariam, Maged Kharouba, Tamara Gligoric, Sherif Hanafy Mahmoud
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
Subjects:
vancomycin
HPLC
augmented renal clearance
chromatography
Online Access:https://www.mdpi.com/1420-3049/30/5/1062
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