Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin
Objectives. This study aims to study the epidemiological and geographic characteristics of the meningococcal serogroups four years after the introduction of serogroup A meningococcal conjugate vaccine. Methods. This is a prospective, descriptive, analytical study, and it took place from 2016 to 2018...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Advances in Public Health |
| Online Access: | http://dx.doi.org/10.1155/2020/1932940 |
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| author | Togbemabou Primous Martial Godjedo Alidehou Jerrold Agbankpe Moussiliou Noël Paraiso Tamegnon Victorien Dougnon Marie Hidjo Lamine Baba-Moussa Honore Bankole |
| author_facet | Togbemabou Primous Martial Godjedo Alidehou Jerrold Agbankpe Moussiliou Noël Paraiso Tamegnon Victorien Dougnon Marie Hidjo Lamine Baba-Moussa Honore Bankole |
| author_sort | Togbemabou Primous Martial Godjedo |
| collection | DOAJ |
| description | Objectives. This study aims to study the epidemiological and geographic characteristics of the meningococcal serogroups four years after the introduction of serogroup A meningococcal conjugate vaccine. Methods. This is a prospective, descriptive, analytical study, and it took place from 2016 to 2018. Cerebrospinal fluid (CSF) samples were taken after the identification of meningitis cases. The samples, thus, taken were sent to the laboratory for culture and identification of Neisseria meningitidis in accordance with WHO standards. Results. Eight hundred and ninety-nine bacterial strains were identified, of which 219 were strains of Neisseria meningitidis. The majority of N. meningitidis-positive samples were from male patients (59.8%) with a median age of 4 (IQR: 1–13). Four of N. meningitidis serogroups were identified, namely, serogroups C (6.8%), W (19.6%), X (1.8%), and A (0.5%). Geographically, 92.7% of the identified N. meningitidis serogroups came from patients who lived in the northern region of the country. The departments most concerned were Alibori (N. meningitidis C (66.7%) and N. meningitidis W (20.9%)); Atacora (N. meningitidis W (41.9%), N. meningitidis X (75.0%), and N. meningitidis C (13.3%)); and Borgou (N. meningitidis W (23.3%)). Conclusion. The results of this study showed that there is an emergence of cases of meningococcal of serogroup C four years after the introduction of MenAfricVac in Benin. These results demonstrated the effectiveness of case-by-case surveillance in detecting small changes in the distribution of serogroups that could have important implications for public health strategies in the coming seasons. |
| format | Article |
| id | doaj-art-1b48dc10ec7c40e394757f6d2bf85fe2 |
| institution | Kabale University |
| issn | 2356-6868 2314-7784 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Public Health |
| spelling | doaj-art-1b48dc10ec7c40e394757f6d2bf85fe22025-02-03T05:53:52ZengWileyAdvances in Public Health2356-68682314-77842020-01-01202010.1155/2020/19329401932940Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in BeninTogbemabou Primous Martial Godjedo0Alidehou Jerrold Agbankpe1Moussiliou Noël Paraiso2Tamegnon Victorien Dougnon3Marie Hidjo4Lamine Baba-Moussa5Honore Bankole6Epidemiological Surveillance Service, Ministry of Public Health, Cotonou, BeninResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, BeninRegional Institute of Public Health, University of Abomey-Calavi, Cotonou, BeninResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, BeninResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Cotonou, BeninLaboratory of Biology and Molecular Typing in Microbiology, Faculty of Science and Technology, University of Abomey-Calavi, Cotonou, BeninEpidemiological Surveillance Service, Ministry of Public Health, Cotonou, BeninObjectives. This study aims to study the epidemiological and geographic characteristics of the meningococcal serogroups four years after the introduction of serogroup A meningococcal conjugate vaccine. Methods. This is a prospective, descriptive, analytical study, and it took place from 2016 to 2018. Cerebrospinal fluid (CSF) samples were taken after the identification of meningitis cases. The samples, thus, taken were sent to the laboratory for culture and identification of Neisseria meningitidis in accordance with WHO standards. Results. Eight hundred and ninety-nine bacterial strains were identified, of which 219 were strains of Neisseria meningitidis. The majority of N. meningitidis-positive samples were from male patients (59.8%) with a median age of 4 (IQR: 1–13). Four of N. meningitidis serogroups were identified, namely, serogroups C (6.8%), W (19.6%), X (1.8%), and A (0.5%). Geographically, 92.7% of the identified N. meningitidis serogroups came from patients who lived in the northern region of the country. The departments most concerned were Alibori (N. meningitidis C (66.7%) and N. meningitidis W (20.9%)); Atacora (N. meningitidis W (41.9%), N. meningitidis X (75.0%), and N. meningitidis C (13.3%)); and Borgou (N. meningitidis W (23.3%)). Conclusion. The results of this study showed that there is an emergence of cases of meningococcal of serogroup C four years after the introduction of MenAfricVac in Benin. These results demonstrated the effectiveness of case-by-case surveillance in detecting small changes in the distribution of serogroups that could have important implications for public health strategies in the coming seasons.http://dx.doi.org/10.1155/2020/1932940 |
| spellingShingle | Togbemabou Primous Martial Godjedo Alidehou Jerrold Agbankpe Moussiliou Noël Paraiso Tamegnon Victorien Dougnon Marie Hidjo Lamine Baba-Moussa Honore Bankole Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin Advances in Public Health |
| title | Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin |
| title_full | Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin |
| title_fullStr | Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin |
| title_full_unstemmed | Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin |
| title_short | Epidemiological Characteristics of Meningococcal Meningitis (2016 to 2018) Four Years after the Introduction of Serogroup A Meningococcal Conjugate Vaccine in Benin |
| title_sort | epidemiological characteristics of meningococcal meningitis 2016 to 2018 four years after the introduction of serogroup a meningococcal conjugate vaccine in benin |
| url | http://dx.doi.org/10.1155/2020/1932940 |
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