Metabolic shifts in lipid utilization and reciprocal interactions within the lung metastatic niche of triple-negative breast cancer revealed by spatial multi-omics

Metabolic shifts in lipid utilization and reciprocal interactions within the lung metastatic niche of triple-negative breast cancer revealed by spatial multi-omics

Abstract The Triple-Negative Breast Cancer (TNBC) subtype constitutes 15-20% of breast cancer cases and is associated with the poorest clinical outcomes. Distant metastasis, particularly to the lungs, is a major contributor to the high mortality rates in breast cancer patients. Despite this, there h...

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Main Authors: Jung-Yu Kan, Hsiao-Chen Lee, Ming-Feng Hou, Hung-Pei Tsai, Shu-Fang Jian, Chao-Yuan Chang, Pei-Hsun Tsai, Yi-Shiuan Lin, Ying-Ming Tsai, Kuan-Li Wu, Yung-Chi Huang, Ya-Ling Hsu
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07205-4
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https://doi.org/10.1038/s41419-024-07205-4

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