Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans
Objectives. To elucidate whether consumption of two Chinese liquors, tea-flavor liquor (TFL) and traditional Chinese liquor (TCL) have protective effects on cardiovascular disease (CVD) risk factors in healthy human subjects. Methods. Forty-five healthy subjects (23 men, 22 women), aged 23–28, were...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/2012/372143 |
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| author | Ju-Sheng Zheng Jing Yang Tao Huang Xiao-Jie Hu Ming Luo Duo Li |
| author_facet | Ju-Sheng Zheng Jing Yang Tao Huang Xiao-Jie Hu Ming Luo Duo Li |
| author_sort | Ju-Sheng Zheng |
| collection | DOAJ |
| description | Objectives. To elucidate whether consumption of two Chinese liquors, tea-flavor liquor (TFL) and traditional Chinese liquor (TCL) have protective effects on cardiovascular disease (CVD) risk factors in healthy human subjects. Methods. Forty-five healthy subjects (23 men, 22 women), aged 23–28, were recruited and randomized into two groups: TFL and TCL, and consumed 30 mL/day (45% (v/v) alcohol) of either liquor for 28 days. Results. Serum high-density lipoprotein cholesterol/low-density lipoprotein cholesterol (HDL-C/LDL-C) and apolipoprotein A1 were significantly increased, and total cholesterol (TC) and TC/HDL-C were significantly decreased after the intervention in both groups (P<0.05). Serum uric acid (P=0.004 for TFL, P=0.001 for TCL), glucose (P<0.001 for TFL, P<0.001 for TCL) and endothelial adhesion molecules (P<0.05) were significantly decreased after the intervention. ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05). Conclusions. TFL and TCL consumption had protective effects on CVD risk factors in young humans. However, the results were valid only for 28 days, and that the possibility of adverse effect (liver, kidney) of chronic alcohol consumption should be considered. |
| format | Article |
| id | doaj-art-1b120b44e71d4cd386b0aed8d63fb593 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-1b120b44e71d4cd386b0aed8d63fb5932025-02-03T06:11:48ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/372143372143Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young HumansJu-Sheng Zheng0Jing Yang1Tao Huang2Xiao-Jie Hu3Ming Luo4Duo Li5Department of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, ChinaCentre of Nutrition and Food Safety, APCNS, 866 Yuhangtang Road, Hangzhou 310058, ChinaDepartment of Food Science and Nutrition, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, ChinaObjectives. To elucidate whether consumption of two Chinese liquors, tea-flavor liquor (TFL) and traditional Chinese liquor (TCL) have protective effects on cardiovascular disease (CVD) risk factors in healthy human subjects. Methods. Forty-five healthy subjects (23 men, 22 women), aged 23–28, were recruited and randomized into two groups: TFL and TCL, and consumed 30 mL/day (45% (v/v) alcohol) of either liquor for 28 days. Results. Serum high-density lipoprotein cholesterol/low-density lipoprotein cholesterol (HDL-C/LDL-C) and apolipoprotein A1 were significantly increased, and total cholesterol (TC) and TC/HDL-C were significantly decreased after the intervention in both groups (P<0.05). Serum uric acid (P=0.004 for TFL, P=0.001 for TCL), glucose (P<0.001 for TFL, P<0.001 for TCL) and endothelial adhesion molecules (P<0.05) were significantly decreased after the intervention. ADP-induced whole blood platelet aggregation was also significantly decreased after the intervention in both TFL and TCL groups (P<0.05). Conclusions. TFL and TCL consumption had protective effects on CVD risk factors in young humans. However, the results were valid only for 28 days, and that the possibility of adverse effect (liver, kidney) of chronic alcohol consumption should be considered.http://dx.doi.org/10.1100/2012/372143 |
| spellingShingle | Ju-Sheng Zheng Jing Yang Tao Huang Xiao-Jie Hu Ming Luo Duo Li Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans The Scientific World Journal |
| title | Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans |
| title_full | Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans |
| title_fullStr | Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans |
| title_full_unstemmed | Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans |
| title_short | Effects of Chinese Liquors on Cardiovascular Disease Risk Factors in Healthy Young Humans |
| title_sort | effects of chinese liquors on cardiovascular disease risk factors in healthy young humans |
| url | http://dx.doi.org/10.1100/2012/372143 |
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