People with high HIV viral load within risk networks: who are these people and who refers them best?
Introduction: Viral load is one of the most important determinants for HIV transmission. Identification of people with high viral load (PHVL) can be effective in limiting onward HIV transmission. In order to improve the identification of these individuals within risk networks, we determined a) the...
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The Journal of Infection in Developing Countries
2019-07-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/11273 |
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| author | Anna Korobchuk Hayk Davtyan Olga Denisiuk Rony Zachariah Georgios K Nikolopoulos Dimitrios Paraskevis Britt Skaathun John Schneider Tetyana I Vasylyeva Leslie D Williams Pavlo Smyrnov Samuel R Friedman |
| author_facet | Anna Korobchuk Hayk Davtyan Olga Denisiuk Rony Zachariah Georgios K Nikolopoulos Dimitrios Paraskevis Britt Skaathun John Schneider Tetyana I Vasylyeva Leslie D Williams Pavlo Smyrnov Samuel R Friedman |
| author_sort | Anna Korobchuk |
| collection | DOAJ |
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Introduction: Viral load is one of the most important determinants for HIV transmission. Identification of people with high viral load (PHVL) can be effective in limiting onward HIV transmission. In order to improve the identification of these individuals within risk networks, we determined a) the number of PHVL recruited through risk networks b) their socio-demographic, behavioural and clinical characteristics and c) the characteristics of individuals who referred these PHVL to the study.
Methodology: From November 2013 to March 2016, in Odessa, Ukraine, Transmission Reduction Intervention Project (TRIP) was implemented to identify people recently infected with HIV within the risk networks of “seeds” and “venues” where they engaged in risk behaviour.
Results: TRIP identified 53 PHVL, of whom 32 (60%) injected drugs; 42 (79%) were unaware of their HIV status; 25 (47%) had more than one sex partner, and only 14 (26%) were using condoms. There were 164 people who referred individuals into the study; 33 of them (20%) referred PHVL. In terms of referrers, those with lower than secondary level of education, not living with a sex partner, and reporting regular condom use were significantly more likely (p < 0.05) to refer PHVL. Most PHVL (38, 72%) and their referrers (27, 82%) were found through venues.
Conclusions: In Odessa city, PHVL are at high risk of transmitting HIV as the majority inject drugs, do not know their HIV status, and have unprotected sex and/or multiple partners. Targeting these individuals for HIV prevention, harm reduction and initiation of antiretroviral treatment (ART) is urgent.
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| format | Article |
| id | doaj-art-1b0490e652f44f94b15c36cd664af4e3 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2019-07-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-1b0490e652f44f94b15c36cd664af4e32025-08-20T02:27:05ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802019-07-011307.110.3855/jidc.11273People with high HIV viral load within risk networks: who are these people and who refers them best?Anna Korobchuk0Hayk Davtyan1Olga Denisiuk2Rony Zachariah3Georgios K Nikolopoulos4Dimitrios Paraskevis5Britt Skaathun6John Schneider7Tetyana I Vasylyeva8Leslie D Williams9Pavlo Smyrnov10Samuel R Friedman11Alliance for Public Health, Kyiv, UkraineTB Research and Prevention Center, Yerevan, ArmeniaAlliance for Public Health, Kyiv, UkraineSpecial Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Geneva, SwitzerlandMedical School, University of Cyprus, Nicosia, CyprusDepartment of Hygiene Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, GreeceDivision of Global Public Health, University of California, San Diego, California, United StatesDepartment of Medicine and Center for HIV Elimination, University of Chicago, Chicago, United StatesDepartment of Zoology, University of Oxford, Oxford, United KingdomNational Development and Research Institutes, Department of Population Health, NYU Medical School, New York, United StatesAlliance for Public Health, Kyiv, UkraineNational Development and Research Institutes, Department of Population Health, NYU Medical School, New York, United States Introduction: Viral load is one of the most important determinants for HIV transmission. Identification of people with high viral load (PHVL) can be effective in limiting onward HIV transmission. In order to improve the identification of these individuals within risk networks, we determined a) the number of PHVL recruited through risk networks b) their socio-demographic, behavioural and clinical characteristics and c) the characteristics of individuals who referred these PHVL to the study. Methodology: From November 2013 to March 2016, in Odessa, Ukraine, Transmission Reduction Intervention Project (TRIP) was implemented to identify people recently infected with HIV within the risk networks of “seeds” and “venues” where they engaged in risk behaviour. Results: TRIP identified 53 PHVL, of whom 32 (60%) injected drugs; 42 (79%) were unaware of their HIV status; 25 (47%) had more than one sex partner, and only 14 (26%) were using condoms. There were 164 people who referred individuals into the study; 33 of them (20%) referred PHVL. In terms of referrers, those with lower than secondary level of education, not living with a sex partner, and reporting regular condom use were significantly more likely (p < 0.05) to refer PHVL. Most PHVL (38, 72%) and their referrers (27, 82%) were found through venues. Conclusions: In Odessa city, PHVL are at high risk of transmitting HIV as the majority inject drugs, do not know their HIV status, and have unprotected sex and/or multiple partners. Targeting these individuals for HIV prevention, harm reduction and initiation of antiretroviral treatment (ART) is urgent. https://jidc.org/index.php/journal/article/view/11273UkraineKey populationsHigh viral loadRisk networkpeople living with HIV (PLWH) |
| spellingShingle | Anna Korobchuk Hayk Davtyan Olga Denisiuk Rony Zachariah Georgios K Nikolopoulos Dimitrios Paraskevis Britt Skaathun John Schneider Tetyana I Vasylyeva Leslie D Williams Pavlo Smyrnov Samuel R Friedman People with high HIV viral load within risk networks: who are these people and who refers them best? Journal of Infection in Developing Countries Ukraine Key populations High viral load Risk network people living with HIV (PLWH) |
| title | People with high HIV viral load within risk networks: who are these people and who refers them best? |
| title_full | People with high HIV viral load within risk networks: who are these people and who refers them best? |
| title_fullStr | People with high HIV viral load within risk networks: who are these people and who refers them best? |
| title_full_unstemmed | People with high HIV viral load within risk networks: who are these people and who refers them best? |
| title_short | People with high HIV viral load within risk networks: who are these people and who refers them best? |
| title_sort | people with high hiv viral load within risk networks who are these people and who refers them best |
| topic | Ukraine Key populations High viral load Risk network people living with HIV (PLWH) |
| url | https://jidc.org/index.php/journal/article/view/11273 |
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