Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients

<strong>Background:</strong> atherosclerosis is a disease of the general metabolism, with damage to the vascular endothelium, which has led to multiple researches using the atherometric system. <br /><strong>Objective:</strong> to characterize and compare the atheroscle...

Full description

Saved in:
Bibliographic Details
Main Authors: Halina Pérez Álvarez, José Fernández-Brito Rodríguez
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2022-08-01
Series:Revista Finlay
Subjects:
Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/1160
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832577440044548096
author Halina Pérez Álvarez
José Fernández-Brito Rodríguez
author_facet Halina Pérez Álvarez
José Fernández-Brito Rodríguez
author_sort Halina Pérez Álvarez
collection DOAJ
description <strong>Background:</strong> atherosclerosis is a disease of the general metabolism, with damage to the vascular endothelium, which has led to multiple researches using the atherometric system. <br /><strong>Objective:</strong> to characterize and compare the atherosclerotic lesion with the use of the atherometric system in the coronary arteries of deceased patients with medico-legal autopsies according to age group. <br /><strong>Methods:</strong> an applied, descriptive, longitudinal and prospective research was carried out. The universe consisted of 183 autopsies, consecutively from the Institute of Legal Medicine, from 2018 to 2019 and the population of 108 deceased divided by age groups. The operationalized variables were the main arterial sectors that supply the heart. The atherometric system was applied to the right and left coronary arteries in their anterior descending and circumflex branches. <br /><strong>Results:</strong> fatty streaks were found in all the arteries of those less than 20 years of age, fibrous plaque in the right coronary artery and anterior descending artery in those between 21 and 40 years of age, and severe plaque in the group between 41 and 60 years of age. Arithmetic means and standard deviations increased with age for all variables. There was a correlation of fatty streaks between the three arteries in the group from 21 to 40, in the group from 41 to 60 between the right coronary artery and the circumflex artery, and a marked correlation between the circumflex artery and the anterior descending artery for fibrous plaques in the group from 41 to 60 years old. 60 years. <br /><strong>Conclusions:</strong> the atherosclerotic lesion was present in the three arteries, the total number of atherosclerosis increased with age, with fibrous plaques appearing from the second decade of life, severe plaques were not observed before the age of 40, and the use of atherometric system turned out to be a useful tool for the study of atherosclerosis.
format Article
id doaj-art-1ae15d5f71eb4aaba04e7d9e489a8aa5
institution Kabale University
issn 2221-2434
language Spanish
publishDate 2022-08-01
publisher Universidad de las Ciencias Médicas de Cienfuegos
record_format Article
series Revista Finlay
spelling doaj-art-1ae15d5f71eb4aaba04e7d9e489a8aa52025-01-30T21:22:01ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342022-08-01123252261584Pathomorphological Study of Coronary Atherosclerosis in Deceased PatientsHalina Pérez Álvarez0José Fernández-Brito Rodríguez1Instituto de Medicina Legal. La Habana.Centro de Investigación y Referencia de Aterosclerosis. La Habana.<strong>Background:</strong> atherosclerosis is a disease of the general metabolism, with damage to the vascular endothelium, which has led to multiple researches using the atherometric system. <br /><strong>Objective:</strong> to characterize and compare the atherosclerotic lesion with the use of the atherometric system in the coronary arteries of deceased patients with medico-legal autopsies according to age group. <br /><strong>Methods:</strong> an applied, descriptive, longitudinal and prospective research was carried out. The universe consisted of 183 autopsies, consecutively from the Institute of Legal Medicine, from 2018 to 2019 and the population of 108 deceased divided by age groups. The operationalized variables were the main arterial sectors that supply the heart. The atherometric system was applied to the right and left coronary arteries in their anterior descending and circumflex branches. <br /><strong>Results:</strong> fatty streaks were found in all the arteries of those less than 20 years of age, fibrous plaque in the right coronary artery and anterior descending artery in those between 21 and 40 years of age, and severe plaque in the group between 41 and 60 years of age. Arithmetic means and standard deviations increased with age for all variables. There was a correlation of fatty streaks between the three arteries in the group from 21 to 40, in the group from 41 to 60 between the right coronary artery and the circumflex artery, and a marked correlation between the circumflex artery and the anterior descending artery for fibrous plaques in the group from 41 to 60 years old. 60 years. <br /><strong>Conclusions:</strong> the atherosclerotic lesion was present in the three arteries, the total number of atherosclerosis increased with age, with fibrous plaques appearing from the second decade of life, severe plaques were not observed before the age of 40, and the use of atherometric system turned out to be a useful tool for the study of atherosclerosis.https://revfinlay.sld.cu/index.php/finlay/article/view/1160aterosclerosisenfermedad de la arteria coronariaautopsia
spellingShingle Halina Pérez Álvarez
José Fernández-Brito Rodríguez
Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
Revista Finlay
aterosclerosis
enfermedad de la arteria coronaria
autopsia
title Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
title_full Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
title_fullStr Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
title_full_unstemmed Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
title_short Pathomorphological Study of Coronary Atherosclerosis in Deceased Patients
title_sort pathomorphological study of coronary atherosclerosis in deceased patients
topic aterosclerosis
enfermedad de la arteria coronaria
autopsia
url https://revfinlay.sld.cu/index.php/finlay/article/view/1160
work_keys_str_mv AT halinaperezalvarez pathomorphologicalstudyofcoronaryatherosclerosisindeceasedpatients
AT josefernandezbritorodriguez pathomorphologicalstudyofcoronaryatherosclerosisindeceasedpatients