Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway
Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. The goal of the current study is to inve...
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-01-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2024-1083 |
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| author | Nazir Nausheen Waqar Arbaz Zaib Khan Amir Ali Khan Ayaz Aziz Tariq Alasmari Abdullah F. |
| author_facet | Nazir Nausheen Waqar Arbaz Zaib Khan Amir Ali Khan Ayaz Aziz Tariq Alasmari Abdullah F. |
| author_sort | Nazir Nausheen |
| collection | DOAJ |
| description | Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. The goal of the current study is to investigate the antiangiogenic potential of Elaeagnus umbellata (E. umbellata) by using chorioallantoic membrane (CAM) assay and molecular docking. |
| format | Article |
| id | doaj-art-1aaa588c785c447b9b10d0ac3593391f |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-1aaa588c785c447b9b10d0ac3593391f2025-01-20T11:09:04ZengDe GruyterOpen Medicine2391-54632025-01-0120149872610.1515/med-2024-1083Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathwayNazir Nausheen0Waqar Arbaz1Zaib Khan Amir2Ali Khan Ayaz3Aziz Tariq4Alasmari Abdullah F.5Department of Biochemistry, University of Malakand, Chakdara Dir Lower18800, PakistanDepartment of Biochemistry, University of Malakand, Chakdara Dir Lower18800, PakistanDepartment of Biochemistry, University of Malakand, Chakdara Dir Lower18800, PakistanDepartment of Biotechnology, University of Malakand, Chakdara Dir Lower18800, PakistanLaboratory of Animal Health Food Hygiene and Quality, University of Ioannina, Arta, GreeceDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaAnti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. The goal of the current study is to investigate the antiangiogenic potential of Elaeagnus umbellata (E. umbellata) by using chorioallantoic membrane (CAM) assay and molecular docking.https://doi.org/10.1515/med-2024-1083elaeagnus umbellataantiangiogenic effectcam assaymolecular docking |
| spellingShingle | Nazir Nausheen Waqar Arbaz Zaib Khan Amir Ali Khan Ayaz Aziz Tariq Alasmari Abdullah F. Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway Open Medicine elaeagnus umbellata antiangiogenic effect cam assay molecular docking |
| title | Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway |
| title_full | Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway |
| title_fullStr | Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway |
| title_full_unstemmed | Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway |
| title_short | Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway |
| title_sort | antiangiogenic potential of elaeagnus umbellata extracts and molecular docking study by targeting vegfr 2 pathway |
| topic | elaeagnus umbellata antiangiogenic effect cam assay molecular docking |
| url | https://doi.org/10.1515/med-2024-1083 |
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