Mesaconic acid as a key metabolite with anti-inflammatory and anti-aging properties produced by Lactobacillus plantarum 124 from centenarian gut microbiota

Mesaconic acid as a key metabolite with anti-inflammatory and anti-aging properties produced by Lactobacillus plantarum 124 from centenarian gut microbiota

Abstract The gut microbiota of centenarians plays a vital role in promoting healthy longevity. We performed a cross-sectional study of 224 people from Jiaoling, China, which is globally recognised for the longevity of its residents. Compared with younger people, centenarians showed significantly inc...

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Main Authors: Lei Wu, Hongxin He, Tingting Liang, Guowei Du, Longyan Li, Haojie Zhong, Ying Li, Jinke Zhang, Ning Chen, Tong Jiang, Juan Yang, Jiangyan Wang, Shuo Feng, Shenghua Lu, Hui Zhao, Qihui Gu, He Gao, Guanghui Li, Wenrui Xie, Lihao Wu, Qingping Wu, Xinqiang Xie, Xingxiang He
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-025-00812-9
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https://doi.org/10.1038/s41522-025-00812-9

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