Nanoparticle-mediated targeting of PGC-1α reveals critical metabolic pathways in bladder cancer metastasis

Abstract Metastatic bladder cancer is characterized by its aggressive behavior and complex molecular mechanisms that remain largely undefined. This study explores the therapeutic potential of targeting peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) using liposomal nano...

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Bibliographic Details
Main Authors: Zhenghua Liu, Peng Xin, Weiwei Wu, Mingyue Jin, Yang Du, Yuanjun Jiang, Tao Liu, Hao Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08174-w
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