Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis

Abstract Background Nonadherence to medication is a prevalent issue among patients with type 2 diabetes mellitus (T2DM). The family doctor system promotes continuous, integrated, and personalized primary care, which may improve medication adherence. However, more evidence is needed regarding causal...

Full description

Saved in:
Bibliographic Details
Main Authors: Xichen Tong, Haiyan Zou, Luying Zhang, Wen Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Public Health
Subjects:
Online Access:https://doi.org/10.1186/s12889-025-21656-0
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832571217165418496
author Xichen Tong
Haiyan Zou
Luying Zhang
Wen Chen
author_facet Xichen Tong
Haiyan Zou
Luying Zhang
Wen Chen
author_sort Xichen Tong
collection DOAJ
description Abstract Background Nonadherence to medication is a prevalent issue among patients with type 2 diabetes mellitus (T2DM). The family doctor system promotes continuous, integrated, and personalized primary care, which may improve medication adherence. However, more evidence is needed regarding causal association between family doctor system and medication adherence. This study is to assess the impact of the family doctor system on medication adherence among T2DM patients. Methods This cohort study utilized data between 2014 and 2019 from three separate administrative databases of an eastern city in China. Adult patients with T2DM who continuously registered with family doctors from 2015 to 2019 (n = 18,841) were assigned to the intervention group, while those who never registered during this period (n = 1,429) were classified as the control group. A difference-in-differences design was employed to compare medication adherence between registered and unregistered T2DM patients after the first stage of family doctor system in 2015 and the second stage in 2018. Propensity score matching was applied to ensure the robustness. The mean proportion of days covered (PDC), and proportion of patients with good adherence (PDC ≥ 80%) were the outcomes of interest. All recommended T2DM medications were included to calculate PDC. Results Compared to the unregistered group, PDC across all institutions for registered patients increased by 5.0% (p < 0.001) after the first stage of family doctor system, and by 5.9% (p < 0.001) after the second stage. The proportion of patients with good adherence increased by 9.5% (p < 0.001) and by 11.8% (p < 0.001) after two stages, respectively. The adherence improvement was more pronounced in community health centers. However, the overall good adherence rate among registered patients in 2019 remained relatively low, reaching only 59.77%. Conclusions The family doctor system significantly improved medication adherence among T2DM patients by providing patient-centered, continuous, and integrated primary services, especially in community health centers. Nevertheless, further efforts should be made to enhance medication adherence.
format Article
id doaj-art-1a7973baf18a4e83bffe4ef8974852b9
institution Kabale University
issn 1471-2458
language English
publishDate 2025-01-01
publisher BMC
record_format Article
series BMC Public Health
spelling doaj-art-1a7973baf18a4e83bffe4ef8974852b92025-02-02T12:45:31ZengBMCBMC Public Health1471-24582025-01-012511910.1186/s12889-025-21656-0Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysisXichen Tong0Haiyan Zou1Luying Zhang2Wen Chen3School of Public Health, Fudan UniversityInstitutional Review Board, Huashan Hospital, Fudan UniversitySchool of Public Health, Fudan UniversitySchool of Public Health, Fudan UniversityAbstract Background Nonadherence to medication is a prevalent issue among patients with type 2 diabetes mellitus (T2DM). The family doctor system promotes continuous, integrated, and personalized primary care, which may improve medication adherence. However, more evidence is needed regarding causal association between family doctor system and medication adherence. This study is to assess the impact of the family doctor system on medication adherence among T2DM patients. Methods This cohort study utilized data between 2014 and 2019 from three separate administrative databases of an eastern city in China. Adult patients with T2DM who continuously registered with family doctors from 2015 to 2019 (n = 18,841) were assigned to the intervention group, while those who never registered during this period (n = 1,429) were classified as the control group. A difference-in-differences design was employed to compare medication adherence between registered and unregistered T2DM patients after the first stage of family doctor system in 2015 and the second stage in 2018. Propensity score matching was applied to ensure the robustness. The mean proportion of days covered (PDC), and proportion of patients with good adherence (PDC ≥ 80%) were the outcomes of interest. All recommended T2DM medications were included to calculate PDC. Results Compared to the unregistered group, PDC across all institutions for registered patients increased by 5.0% (p < 0.001) after the first stage of family doctor system, and by 5.9% (p < 0.001) after the second stage. The proportion of patients with good adherence increased by 9.5% (p < 0.001) and by 11.8% (p < 0.001) after two stages, respectively. The adherence improvement was more pronounced in community health centers. However, the overall good adherence rate among registered patients in 2019 remained relatively low, reaching only 59.77%. Conclusions The family doctor system significantly improved medication adherence among T2DM patients by providing patient-centered, continuous, and integrated primary services, especially in community health centers. Nevertheless, further efforts should be made to enhance medication adherence.https://doi.org/10.1186/s12889-025-21656-0MedicationAdherencePrimary careFamily doctorDiabetesDifference-in-differences
spellingShingle Xichen Tong
Haiyan Zou
Luying Zhang
Wen Chen
Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
BMC Public Health
Medication
Adherence
Primary care
Family doctor
Diabetes
Difference-in-differences
title Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
title_full Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
title_fullStr Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
title_full_unstemmed Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
title_short Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis
title_sort impact of the family doctor system on medication adherence among type 2 diabetes patients in china a difference in differences analysis
topic Medication
Adherence
Primary care
Family doctor
Diabetes
Difference-in-differences
url https://doi.org/10.1186/s12889-025-21656-0
work_keys_str_mv AT xichentong impactofthefamilydoctorsystemonmedicationadherenceamongtype2diabetespatientsinchinaadifferenceindifferencesanalysis
AT haiyanzou impactofthefamilydoctorsystemonmedicationadherenceamongtype2diabetespatientsinchinaadifferenceindifferencesanalysis
AT luyingzhang impactofthefamilydoctorsystemonmedicationadherenceamongtype2diabetespatientsinchinaadifferenceindifferencesanalysis
AT wenchen impactofthefamilydoctorsystemonmedicationadherenceamongtype2diabetespatientsinchinaadifferenceindifferencesanalysis