Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment.
<h4>Background</h4>T cells producing multiple factors have been shown to be required for protection from disease progression in HIV but we have recently shown this not to be the case in TB. Subjects with active disease had a greater proportion of polyfunctional cells responding to ESAT-6...
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| Main Authors: | James M Young, Ifedayo M O Adetifa, Martin O C Ota, Jayne S Sutherland |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-06-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011237&type=printable |
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