Phenolic-rich extract from Citrus sinensis leaves attenuates diabetic cardiomyopathy in male wistar rats by modulating oxidative stress, hyperlipidemia, and pyroptosis-related gene expression

Phenolic-rich extract from Citrus sinensis leaves attenuates diabetic cardiomyopathy in male wistar rats by modulating oxidative stress, hyperlipidemia, and pyroptosis-related gene expression

Diabetic cardiomyopathy (DCM) is a complication that is closely associated with diabetes mellitus. This study aims to evaluate the effects of free phenolic-rich extract from Citrus sinensis leaves (FPCS) on DCM, and investigate the underlying cardioprotective mechanisms in a type 2 diabetes (T2DM) r...

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Main Authors: Jude Akinyelu, Akinwunmi Oluwaseun Adeoye, Abiodun Aladetuyi, Omodele Ibraheem, Adaora Chinemelum Onodugo, Olapade Samuel Akinlolu, John Adeolu Falode, Olabisi Tajudeen Obafemi, Toluwase Hezekiah Fatoki
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Food Chemistry Advances
Subjects:
Cardioprotection
Hyperglycemia
Inflammatory
Online Access:http://www.sciencedirect.com/science/article/pii/S2772753X24002715
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http://www.sciencedirect.com/science/article/pii/S2772753X24002715

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