The efficacy of colchicine in patients with gout with different missense genetic variants of the <i>ABCG2</i> gene (<i>V12M; rs2231137</i> and <i>Q141K; rs2231142)</i>

The efficacy of colchicine in patients with gout with different missense genetic variants of the <i>ABCG2</i> gene (<i>V12M; rs2231137</i> and <i>Q141K; rs2231142)</i>

Genetic polymorphisms in ABCG2 gene (V12M; rs2231137 and Q141K; rs2231142) in patients with gout may determine the efficacy of colchicine for the prevention of arthritis attacks during the initiation of urate-lowering therapy. These data can be used in the development of a personalized approach for...

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Bibliographic Details
Main Authors: M. S. Eliseev, M. N. Chikina, I. A. Guseva, O. V. Zhelyabina, Ya. I. Kuzmina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2025-04-01
Series:Современная ревматология
Subjects:
gout
colchicine
<i>abcg2</i>
personalized medicine
Online Access:https://mrj.ima-press.net/mrj/article/view/1743
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