From oncogenesis to prognosis: the roles of the immunoproteasome in cancer

The proteasome (prosome, macropain) is a key cellular organelle responsible primarily for protein homeostasis, by degrading damaged or misfolded proteins. Proteasome-processed protein fragments can then be further trimmed and funneled to the major histocompatibility complex class I (MHC-I) antigen p...

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Bibliographic Details
Main Authors: Delphine Béland, Mélissa Viens, Emma Mary Kalin, Marie-Claude Bourgeois-Daigneault
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1603816/full
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