Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM

Oral Fusobacterium nucleatum resists the acidic pH of the stomach due to membrane erucic acid synthesized via enoyl-CoA hydratase-related protein FnFabM

Background and Objective Oral bacteria can translocate to the intestine, and their colonization efficiency is influenced by the gastrointestinal tract pH. Understanding how oral bacteria resist acidic environments is crucial for elucidating their role in gut health and disease.Methods To investigate...

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Bibliographic Details
Main Authors: Xiaocong Li, Shipeng Zhang, Huafang Sheng, Yan Zhen, Buling Wu, Zhuang Li, Dingqiang Chen, Hongwei Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Journal of Oral Microbiology
Subjects:
Bacterial acid resistance
Fusobacterium nucleatum
FabM
erucic acid C22:1(n9)
in vitro GI tract dynamic ph model
Online Access:https://www.tandfonline.com/doi/10.1080/20002297.2025.2453964
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https://www.tandfonline.com/doi/10.1080/20002297.2025.2453964

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