Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity

Available evidence suggests that trace elements, such as zinc, once thought to have no nutritional relevance, are possibly deficient in large sections of the human population. Conditioned deficiencies have been reported to result from malabsorption syndromes, acrodermatitis enteropathica, alcoholism...

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Main Authors: Michelle M Pluhator, Alan Br Thomson, Richard N Fedorak
Format: Article
Language:English
Published: Wiley 1996-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1996/492792
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author Michelle M Pluhator
Alan Br Thomson
Richard N Fedorak
author_facet Michelle M Pluhator
Alan Br Thomson
Richard N Fedorak
author_sort Michelle M Pluhator
collection DOAJ
description Available evidence suggests that trace elements, such as zinc, once thought to have no nutritional relevance, are possibly deficient in large sections of the human population. Conditioned deficiencies have been reported to result from malabsorption syndromes, acrodermatitis enteropathica, alcoholism, gastrointestinal disease, thermal injury, chronic diseases (eg, diabetes, sickle cell anemia), and in total parenteral nutrition therapy. Awareness that patients with these problems are at risk has led health professionals to focus increasingly on the importance of zinc therapy in the prevention and treatment of deficiency. More recently zinc toxicity and its role in human nutrition and well-being have come under investigation. Reports have focused on the role of zinc toxicity in causes of copper deficiency, changes in the immune system and alterations in blood lipids. As the numerous challenges presented by the study of zinc in human nutrition are met, more appropriate recommendations for dietary and therapeutic zinc intake are being made.
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spelling doaj-art-198f16b0ebab438380a54cdb1f1af4d72025-02-03T01:29:51ZengWileyCanadian Journal of Gastroenterology0835-79001996-01-011029710310.1155/1996/492792Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and ToxicityMichelle M Pluhator0Alan Br Thomson1Richard N Fedorak2Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaDivision of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, CanadaAvailable evidence suggests that trace elements, such as zinc, once thought to have no nutritional relevance, are possibly deficient in large sections of the human population. Conditioned deficiencies have been reported to result from malabsorption syndromes, acrodermatitis enteropathica, alcoholism, gastrointestinal disease, thermal injury, chronic diseases (eg, diabetes, sickle cell anemia), and in total parenteral nutrition therapy. Awareness that patients with these problems are at risk has led health professionals to focus increasingly on the importance of zinc therapy in the prevention and treatment of deficiency. More recently zinc toxicity and its role in human nutrition and well-being have come under investigation. Reports have focused on the role of zinc toxicity in causes of copper deficiency, changes in the immune system and alterations in blood lipids. As the numerous challenges presented by the study of zinc in human nutrition are met, more appropriate recommendations for dietary and therapeutic zinc intake are being made.http://dx.doi.org/10.1155/1996/492792
spellingShingle Michelle M Pluhator
Alan Br Thomson
Richard N Fedorak
Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
Canadian Journal of Gastroenterology
title Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
title_full Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
title_fullStr Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
title_full_unstemmed Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
title_short Clinical Aspects of Trace Elements: Zinc in Human Nutrition – Zinc Deficiency and Toxicity
title_sort clinical aspects of trace elements zinc in human nutrition zinc deficiency and toxicity
url http://dx.doi.org/10.1155/1996/492792
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